References

GENERAL


Ambrose, E. J., and Roe, F. J. C. The Biology of Cancer. London and Princeton, N.J.: D. Van Nostrand, 1966. (Fairly technical)
Berenblum, I. Cancer Research Today. London: Pergamon Press 1967. Written from the scientist's point of view. Reasonably detailed, but makes fairly easy reading. Particularly valuable to someone with a background in biology.
Cameron, C. S. The Truth About Cancer. New York: Collier Books, 1967. A book for the layman written from the point of view of the physician. It has a good deal of information about specific forms of cancer. There is an outstanding section on cancer quackery, and much good advice on things such as breast self-examination.
Foulds, L. Neoplastic Development. London: Academic Press, 1969. The historical review in this book is worth reading by the physician or the biologist for an overview of the field of experimental cancer research. It is written for the specialist rather than the layman.
Leighton, J. The Spread of Cancer. New York and London: Academic Press, 1967. An excellent book on the spread of cancer (metastasis) written for the professional.
McGrady, Pat. The Savage Cell. New York: Basic Books, 1964. Easy reading about cancer research. McGrady is a professional science writer, and it shows. It contains a large amount of information in easily digestible form.
Perez-Tamayo, R. Mechanisms of Disease: An Introduction to Pathology. Philadelphia: W. B. Saunders, 1961. A remarkably concise discussion of tumors, intended for the student of pathology and the specialist. It has a very discriminating synthesis of clinical observation and experimental cancer research.
Shimkin, Michael B. Science and Cancer, Public Health Service Publication No. 1162, 1969. Very easy reading, highly informative, and concise book. It says an awful lot in150 pages.


ANYTHING GROWS

(All highly technical)

Leblond, C. P. "Classification of Cell Populations on the Basis of Their Proliferative Behavior," in Control of Cell Division and the Induction of Cancer, Monograph 14. Bethesda, Md.: National Cancer Institutes, 1964, pp.119-149.
Pilgrim, H. I. "The Kinetics of the organ-specific Metastasis of a Transplantable Reticuloendothelial Tumor." Cancer Research 29(1969): 1200-1205.
The Proliferation and Spread of Neoplastic Cells. Baltimore: Williams and Wilkins, 1968, 794 pages. A collection of papers on the spread and growth of tumors.

WHY TUMORS SEEM WILD


Abercrombie, M., and Ambrose, E. J. "The Surface Properties of Cancer Cells: A Review." Cancer Research 22 (1962):525-548.
Hoffman, J. G., Goltz, H. L., Reinhard, M. C., et al.: "Quantitative Determination of the Growth of a Transplantable Mouse Adenocarcinoma." Cancer Research 3 (1943):237-242.
Huseby, R. A., and Bittner, J. J "Differences in Adrenal Responsiveness to Postcastrational Alteration as Evidenced by Transplanted Adrenal Tissue." Cancer Research 11 (1951): 954-961.
Iversen, 0. H. "Kinetics of Cellular Proliferation and Cell Loss in Human Carcinomas: A Discussion of Methods Available for In vivo Studies." European Journal of Cancer 3 (1967):389-394.
Laird, A. K. "Dynamics of Tumor Growth: Comparison of Growth Rates and Extrapolation of Growth Curve to One Cell." British Journal of Cancer 19 (1965): 278-29I.
Pilgrim, H. I. "Studies of Postcastrational Adrenal Cortical Changes in Parabiotic C3H Female Mice." Cancer Research 21 (1960): 1555-1560.
Steel, G. G., Adams, K., and Barret, J. C. "Analysis of the Cell Population Kinetics of Transplanted Tumors of Widely Differing Growth Rate." British Journal of Cancer 20(1966): 784-800.
Stohlman, F. Jr., ed. The Kinetics of Cellular Proliferation. New York: Grune & Stratton. 1959.
Weiss, P., and Kavanau, J. L. "A Model of Growth and Growth Control in Mathematical Terms. Journal of General Physiology,41 (1957): 1-47.

MAN AS A HOLE


Steinberg, M. "Does Differential Adhesion Govern Self-Assembly Processes in Histogenesis? Equilibrium Configuration and the Emergence of a Heirarchy Among Populations of Embryonic Cells" Journal of Experimental Zoology 173 (1970): 395-434 This is a scientist's way of saying what I have described in this chapter. The answer to his question "Does differential adhesion govern self-assembly processes in histogenesis?" is "yes!" This reference, as you might have guessed from the title, is highly technical.
Pilgrim, H. I. "Relationship of the Selective Metastatic Behavior of Tumors of Reticular Tissues to the Migration Patterns of Their Normal Cells of Origin." Journal of the National Cancer Institute 49 (1972):3-6.

NOT ANOTHER BREAKTHROUGH?

The following two references refer to the work of Rous and Huggins that won them the Nobel Prize. They are both fairly technical.
Rous, F. P. "The Challenge to Man of the Neoplastic Cell" (Nobel Prize Lecture). Cancer Research 27 (1967): 1919-1924; also in Science 157(1967): 24-28.
Huggins, C. B, "Endocrine-induced Regression of Cancers (Nobel Prize Lecture). Cancer Research 27 (1967): 1925-1930.
Oberling, Charles. The Riddle of Cancer. New Haven, Conn.: Yale University Press,1944. This book is written by a French scientist and represents the point of view of some one who believes very strongly that cancer is caused by viruses. It is well written, well translated, and makes fairly easy reading. One of the most interesting parts of the book is his discussion of the series of events that led up to Fibiger winning the Nobel Prize, and the events following that indicated that his results were not repeatable. Oberling retains his objectivity throughout the book despite his being an adherent of the virus theory of cancer.
Watson, J. D. Molecular Biology of the Gene. New York: W. A. Benjamine, 1965. This is a book for students of molecular biology. Two simpler, more readable books are listed below.
Asimov, I. The Genetic Code. New York: New American Library, 1963.
Frankel, E. DNA --Ladder of Life. New York: McGraw-Hill, 1964.

STATISTICS

(All technical)
Cancer Facts and Figures. New York: American Cancer Society, published annually.
"Cancer Registration and Survival in California." Berkeley, Calif.: State of California Department of Public Health, California Tumor Registry, 1963.
Connecticut State Department of Health
1964, "Cancer in Connecticut Mortality Data, 1949-1961,"104 pages.
1967 "Cancer in Connecticut Incidence Characteristics,1935-1962," 97 pages.
1968 "Cancer in Connecticut Survival Experience, 1935-1962," II4 pages.
Cowdry, E. V. Etiology and Prevention of Cancer in Man. New York: Appleton-Century-Crofts, 1968. A compilation of a large amount of statistical data on cancer, classified by the affected organ. The bibliography should be useful to people interested in cancer epidemiology.
Fraumeni, J. F., and Miller, R. W. "Leukemia Mortality: Down-turn Rates in the United States" Science: '55 (1967):
Lilienfeld, A. M., Pedersen, E., and Dowd, J. E. Cancer Epidemiology: Methods of Study. Baltimore: Johns Hopkins Press, 1967, 16 pages.
Pearl, R. Introduction to Medical Biometry and Statistics. W. B. Saunders, 1923. Philadelphia. This book is the classic in its field. It explains the assumptions that statisticians sometimes take for granted.

CHEMICAL CARCINOGENESIS

BerenbLum, I. Cancer Research Today. London: Pergamon Press, 1967. A readable and complete discussion of cancer research. An especially fine section on chemical carcinogenesis, which is the author's specialty.
Herbst, L., Ulfelder, H., Poskanzer, C "Adenocarcinoma of the Vagina; Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women." New England Journal of Medicine 284 (1971): 878-881. (Technical)
Percivall Pott's astute 1775 paper on this subject has been reprinted, thanks to Dr. Michael Potter, in National Cancer Institute Monograph No. 10 (Conference: Biology of Cutaneous Cancer). It makes very interesting reading.
Price, J. M. Etiology of Bladder Cancer in Benign and Malignant Tumors of the Urinary Bladder Edited by E. Maltry. Flushing, N.Y.: Medical Examination Publishing Co., 1971, pp.189_261. This is an excellent and complete review of the causes of cancer of the bladder. While it is a technical paper, it is fairly easy to read, It contains a very complete bibliography.
Shabad, L. M. Geography and Cancer of the Stomach in the U.S.S.R." Carcinoma of the Alimentary Tract. Edited by Walter J. Burdette,1965. (Technical)
Spatz, M., Smith, D. W. E., McDaniel, E.G., Laqueur, G. L. "Role of Intestinal Microorganisms in Determining Cycasin Toxicity." Proceedings of the Society for Experimental Biology and Medicine 124 (1967): 691-697. Highly technical. An elegant series of experiments that show how intestinal bacteria can convert a harmless substance into a powerful carcinogen.
Symposium sponsored by the International Union Against Cancer. Symposium on Carcinogens of Plant Origin. Cancer Research 28 (1968): Williams & Wilkins. 2233-2396.


TOBACCO IS A DEADLY WEED


McGrady, Pat. The Savage Cell. New York: Basic Books, 1964, 432 pages. His chapter on tobacco and cancer is outstanding.
Smoking and Health -Report of the Advisory Committee to the Surgeon General of the Public Health Service, Washington, D.C.: U.S. Government Printing Office, Health Service Publication No.1103, 1964, 387 pages. A well-documented book written by a committee.

RADIATION AND CANCER

(All highly technical)

Blum, H. F. Carcinogenesis By Ultraviolet Light. Princeton, N.J.: Princeton University Press, 1959.
Brues, A. M. "Critique of the Linear Theory of Carcinogenesis." Science 128 (1958): 693-699. A very thorough discussion in which the author concludes that the relationship of radiation to carcinogenesis is probably not linear, and that there is probably a threshold below which no leukemia is induced.
Folley, J. H., Borges, W., and Yamawaki, T. "Incidence of Leukemia in Survivors of the Atomic Bomb in Hiroshima and Nagasaki, Japan." American Journal of Medicine (1952): 311-321.
Fraumeni, J. F., Miller, R. W. "Epidemiology of Human Leukemia: Recent Observations." Journal of National Cancer Institute 38 (1966): 593-605. A very thorough discussion of leukemia statistics.
Furth, J., and Upton, A. C. "Vertebrate Radiobiology: Histopathology and Carcinogenesis." Annual Review of Nuclear Science 3 (1953) 303-337. A fairly complete review of the subject.
Hemplemann, L. H., Pifer, J. W., Burke, G. J., et al.: "Neoplasms in Persons Treated with X-rays in Infants for Thymic Enlargement. A Report of the Third Follow-up Survey." Journal of National Cancer Institute 38 (1967):317-341. A complete follow-up study of infants that had received thymic irradiation.
Lewis, E. B. "Leukemia, Multiple Myeloma, and Aplastic Anemia in American Radiologists." Science 142 (1963): 1492-1494.
Mays, C. W. "Cancer induction in man from internal radioactivity." Health Physics 25 (1973): 585-592. A delight fully written short summary of the work which has been done on cancer caused by the ingestion, inhalation or injection of radioactive substances. Mays is one of a group of quiet people who are providing the accurate information which the public need to become justifiably outraged.
Mays, C. W., and Lloyd, R. D. "Bone Sarcoma Risk for 90Sr." 1971, in press.
Moloney, W. C., and Lange, R. D. "Leukemia in Atomic Bomb Survivors II. Observations on Early Phases of Leukemia." Hematology 9 (1954): 663-684.
Simpson, C. L., and Hemp]emann, L. H. "The Association of Tumors and Roentgen Ray Treatment of the Thorax in Infancy." Cancer 10 (1957): 42-56.

EMBRYOS, GENES, AND CANCER

(All technical)

Gurdon, J. B. Transplanted Nuclei and Cell Differentiation. Scientific American 219 (1968): 24-35.
Kleinsmith, L. J., and Pierce, G. B. "Multipotentiality of Single Embryonal Carcinoma Cells." Cancer Research 24 (1964):1544-1551.
Stevens, L. C. "Experimental Production of Testicular Teratomas in Mice of Strains 129, A /He, and Their F1 hybrids." Journal of National Cancer Institute 44 (1970): 923-929.
Symposium sponsored by the American Cancer Society. "The Developmental Biology of Neoplasia." Cancer Research 28(1967): 1797-1914.

Much of the work on chalones has been done by W. S. Bullough at the University of London and 0. H. Iversen at the University of Oslo. A good overall view can be found in the book edited by Teir, H., and Rytomaa, T. Control of Cellular Growth in Adult Organisms. London and New York, Academic Press, 1964.
Chalones: Concepts and Current Researches, National Cancer Institute Monograph 38, July 1973. DHEW Publication No. (NIH) 73-425. This volume is a series of up-to-date articles on chalones. It also has a good historical introduction. The papers are highly technical.

YES, VIRGINIA, VIRUSES DO CAUSE CANCER

Clemens, S. (Twain, M.) Tom Sawyer, 1875. The classic paper on wart treatment.

(The following are all highly technical)
Giertsen, J. C. "Malignant Testicular Tumors Following Mumps Orchitis." Acta Pathologica et Microbiologica Scandinavica 42 (1957): 7-14.
Gross, L. Oncogenic Viruses. New York: Pergamon Press, 1961.
Melnick, J. L. 1965 "The Papovavirus Group," in Viral and Rickettsial Infections of Man, 4th ed. Edited by Horsfall and Tanner. Philadelphia: J. B. Lippincott Co., 1965, pp. 841-859.
Prehn, R. T. "Tumor-specific Antigens of Putatively Nonviral Tumors." Cancer Research 28 (1968): I326-I33O.
Rowe, Wallace P. "1973 Genetic Factors in the Natural History of Murine Leukemia Virus Infection." Cancer Research 33: 3061-3068. A fine, highly technical history and discussion of the cancer-virus-gene problem. Rowe and his group perform highly competent virus-cancer research at the National Institute of Allergy and Infectious Diseases; a stone's throw from the political hubbub of the National Cancer Institute.
Symposium sponsored by the American Cancer Society. "Conference on Tumor-specific Antigens." Cancer Research 28(1967): 1275-1459.

EVERYTHING YOU WANT TO KNOW ABOUT SEX AND CANCER

Elliott, R. I. K. "Carcinoma of the Cervix --Basic Research." The Prevention of Cancer. Edited by Raven and Roe. London: Appleton-Century-Crofts, 1967, pp.281-290.
Fergusson, J. D. "Cancer of the Prostate." In The Prevention of Cancer. Edited by Raven and Roe. London: Appleton-Century-Crofts, 1967, pp. 257-261.
Griffiths, J. D. "Carcinoma of the Penis." In The Prevention of Cancer. Edited by Raven an Roe. London: Appleton-Century-Crofts, 1967, pp. 262-264.
Mirra, A. P., Cole, P., and MacMahon, B., "Breast Cancer in an Area of High Parity: Sao Paulo, Brazil." Cancer Research 31 (1971): 77-83.
Rotkin, I. D. "Adolescent Coitus and Cervical Cancer: Associations of Related Events with Increased Risk." Cancer Research 27 (1967): 603-617.
Steele, R., Lees, R F. M., and Kraus, A. S. "Sexual Factors in the Epidemiology of Cancer of the Prostate." Journal of Chronic Disease 24 (1971): 29-37. Wynder, E. L., Cornfield, J., and Schroff, P. D. "A Study of Environmental Factors in Carcinoma of the Cervix." American Journal of Obstetrics and Gynecology 68 (1954)1016-1052.
Wynder, F. L., Bross, I. J., and Hirayam, T. "A Study of the Epidemiology of Cancer of the Breast." Cancer 12 (1960):559-601.

CANCER IMMUNOLOGY

_Conceptual Advances in Immunology and Oncology. New York: Harper & Row. Hoeber Medical Division, 1963. This volume contains the papers from a symposium on "Fundamental Cancer Research" held at the M. D. Anderson Hospital and Tumor Institute in Houston, Texas. Among many interesting (and very technical) articles are papers by Hans 0. Sjogren (Sweden) and by Karl Habel (U.S.A.), who independently discovered the immunologic differences in polyoma-induced tumors. There is also a paper by R. H. Wilson et al. on treating human cancer with concentrated antibodies.
Jacobs, Barbara B., and Huseby, R. A. "Growth of Tumors in Allogeneic Hosts Following Organ Culture Explantation." Transplantations (1967): 410-419.

IS CANCER INHERITED?

Genetics and Cancer. Austin: University of Texas, 1959. Many papers on genetics and cancer.
Macklin, M. T. "Genetic Considerations in Human Breast and Gastric Cancer." In Genetics and Cancer. Austin, University of Texas, 1959, pp. 408-425.
Stern, C. Principles of Human Genetics. San Francisco: W.H. Freeman and Co., 1960. This is a textbook of human genetics. It is fairly easy to read.
Tokuhata, G. K. "Familial Factors in Lung Cancer and Smoking." In Genetics and the Epidemiology of Chronic Diseases. Washington, D.C., U.S. Dept. of Health, Education, and Welfare, 1965, pp.339-353
Woolf, C. M. Investigations on Genetic Aspects of Carcinoma of the Stomach and Breast, vol.2, pp. 265-350. Berkeley: University of California Press, 1955.

WHY SOME TUMORS SPREAD

Greene, H. S. N., and Harvey, F. K. "The Relationship Between the Dissemination of Tumor Cells and the Distribution of Metastases." Cancer Research 24 (1964): 799-811.
Kinsey, D. L. "An Experimental Study of Preferential Metastasis." Cancer 13 (1960): 674-676.
Leighton, J. The Spread of Cancer Pathogenesis, Experimental Methods, Interpretations. New York: Academic Press, 1967
Pilgrim, H. I. "The Kinetics of the Organ-specific Metastasis of a Transplantable Reticuloendothelial Tumor." Cancer Research 29(1969): 1200-1205.
Wallace, A. C. "Metastasis as an Aspect of Cell Behavior." In Canadian Cancer Conference, Proceedings of the Canadian Cancer Research Conference in 1960, vol. 4, pp. 139-165. New York: Academic Press, 1961.
Weiss, P., and Andres, G. "Experiments on the Fate of Embryonic Cells 'Chick' Disseminated by the Vascular Route." Journal of Experimental Zoology 121(1952): 449-487.
Willis, R. A. The Spread of Tumors in the Human Body. London: Butterworth & Co., 1952.
Zeidman, I. "Metastasis: A Review of Recent Advances." Cancer Research 17(1957): 157-162.

IS IT CANCER, DOCTOR?

(Both highly technical)
Clark, W. H., Jr., From, L., Bernadino, E. A., et al: Histogenesis and Biologic Behavior of Primary Human Malignant Melanomas 0f the Skin." Cancer Research 29(1969): 705-726.
Wintrobe, M. M. Clinical Hematology, 6th ed. Philadelphia: Lea & Febiger,1967.

THE DOCTOR SAID "HE'D BE DEAD IN A YEAR" --AND HE ISN'T

The following two books document a goodly number of cases of "proved" cancer that either went into long remission, or where the cancers disappeared completely. Many of the cases that have undergone spontaneous remissions and cures have been some of the rarer types of cancer in children, the so called embryonic tumors.


Boyd, W. The Spontaneous Regression of Cancer. Springfield, Charles C Thomas, 1966.
Everson, T. C., and Cole, W. H. Spontaneous Regression of Cancer. Philadelphia and London: W. B. Saunders, 1966.

WHEN IN DOUBT, CUT IT OUT!

Ackerman, L. V., and del Regato, J. A. Cancer: Diagnosis, Treatment and Prognosis. St. Louis, Mo.: C. V. Mosby Co.,
Berkson, J., Harrington, S. W., Clagett, 0. T., et al.: "Mortality and Survival in Surgically Treated Cancer of the Breast: A Statistical Summary of Some Experience of the Mayo Clinic." Proceedings of the Staff Meetings of the Mayo Clinic, 1957.
McDivitt, R. W., Stewart, F. W., and Berg, J. W. "Tumors of the Breast." In Atlas of Tumor Pathology, 2nd ser., fascicle 2. Washington, D.C.: Armed Forces Institute of Pathology, 1968. This publication contains the type of information that a pathologist needs to make a diagnosis. There is also a good discussion of the imponderables in treatment, and a table detailing the results of treatment with different types of tumors.

RADICAL SURGERY

Campion, Rosamond. The Invisible Worm. New York. Macmillan Co., 1972. This book tells of the personal experience of a woman with breast cancer. She also discusses the experiences of her acquaintances who have had breast cancer. It is a well-written, well thought-out book. She chose to go to George Crile for a lumpectomy. She summarizes her opinion as follows: "The truth is this: no woman on earth is exactly like any other woman. Even in the thrall of a dread disease, she is unique and must be paid by her doctor the compliment of being allowed partnership, within the proper framework of her illness, in deciding what is the best solution for her own special or even eccentric needs."
Crile, G. A Biological Consideration of Treatment of Breast Cancer. Springfield, Ill.: Charles C. Thomas, 1967. Advocates simple surgery and a "common sense" approach to cancer.
Crile, George. What Women Should Know About the Breast Cancer Controversy. New York: Macmillan Co., 1973. I read this book while putting the finishing touches on this manuscript. There was no need to change a word in my book, because Crile's conclusions and mine are almost the same. Crile writes well, and his understanding of surgery is profound. He does not believe in the efficacy of radical mastectomy, and prefers simple mastectomy or modified radical mastectomy. He does not, as has been implied in a newspaper article that I have read, "advocate" lumpectomy except for the woman who is willing to risk her life to save her breast. He believes that the patient has the right to make his or her own decisions. He did point out something which I had completely overlooked: that the amount of money paid to a surgeon by an insurance company is proportional to the amount of work involved rather than the efficacy of the operation. I phoned my local Blue Shield office and found out that a simple mastectomy is twice as lucrative as a lumpectomy or partial mastectomy and that a radical is two and a half times as lucrative as a simple mastectomy.
Fisher, B. "The Surgical Dilemma in the Primary Therapy 0f Invasive Breast Cancer: A Critical Appraisal." Current Problems in Surgery:Chicago: Year Book Medical Publishers, October 1970, 53 pages. A scholarly, complete, and objective review of the literature. This is "must reading" for the surgeon. He concludes that surgeons should continue with their usual method of treatment until the critical trials have been performed; and these trials are long overdue. They have been started in England, and are being started in this country.

LEUKEMIA IN CHILDREN

"Conference on Acute Leukemia and Burkitt's Tumor," Cancer Research 27 (1967): 2414-2660. A series of papers on leukemia and Burkitt's tumor.

Holland, J. F. "Progress in the Treatment of Acute Leukemia, 1966." Perspectives in Leukemia. New York: Grune & Stratton, 1968, pp.217-240.

TO TREAT OR NOT TO TREAT

In the journal Cancer Research, vol.29, no.12 (November 1969) pages 2262-2485, there is a many-authored discussion of the present state of chemotherapy. Good results have been obtained with the following tumors: Choriocarcinoma, Wilms' tumor (a tumor of the kidney that occurs in children), tumors of the testicle, Burkitt's lymphoma (a lymphocytic tumor which also occurs frequently in children), and Hodgkin's disease.

GO TO A CANCER QUACK --IT'S YOUR LIFE

Cameron, C. S. The Truth About Cancer. Englewood Cliffs, N.J.: Prentice Hall, 1956; Also New York: Macmillan Co., 1967. His chapter on the cancer quack is a gem.

PREVENTION IS BETTER

Raven, R. W., Roe, F. J. C., eds. The Prevention of Cancer London: Appleton-Century-Crofts, 1967.

THE MIND AND CANCER

Groddeck, Georg. Das Buch Von Es. Vienna: International Psychoanalytischer Verlag, 1923. This book is available in paperback, in an excellent translation as The Book of the It. New York: New American Library, Mentor Books, 1961. Groddeck has been called the "father of psychosomatic medicine." He was a contemporary of Freud. Although he was a friend and admirer of Freud, he was never a true disciple. He went his own way and made many original observations (see Carl and Sylva Grossman, The Wild Analyst. New York: Dell Publishing Co., 1965). Groddeck has no fancy theoretical constructs to obscure his astute observations. He is a humane physician who is also exquisitely perceptive and an excellent writer. The simplicity of this book is not only deceptive, but seductive. In the words of a young friend of mine. "It's a real mind blower."

THE MIND AND CANCER

Crile, G. Cancer and Common Sense. New York: Viking Press, 1955. This is a wonderful and readable book by a surgeon. It is delightful reading and full of wisdom and under standing. It has raised some hackles by statements such as, "Those responsible for telling the public about cancer have chosen to use the weapon of fear. They have portrayed cancer as an insidious, dreadful, relentless invader. With religious fervor they have fashioned a devil out of cancer. They have bred in a sensitive public a fear that is approaching hysteria. They have created a new disease, cancerphohia, a contagious disease that spreads from mouth to ear. It is possible that today cancerphobia causes more suffering than cancer itself." Page 7.
This book was written at a time surgeons were doing super-radical operations that have now been largely discredited. It is already a classic, and is must reading" for physicians, patients, and anyone who is interested in disease and the human being.
Kubler-Ross, Elisabeth. On Death and Dying. New York: Macmillan Co., 1969. (This is available in paperback) This book is by a psychiatrist who has been working with the terminally ill. It is a very readable book, and should be "must reading" for all physicians and clergymen. It describes how people react to serious illness. One of the underlying themes, which isn't specifically stated, appears to be "Physician, heal thyself." It is a sensitive, wise, and understanding book.I tried to summarize this book in an attempt to give the reader the essence of what is said in it. I found myself removing so many large quotations, that I would feel that I would have had to pay Dr. Kubler-Ross royalties for taking that much. It is not very useful to try to summarize something that is already said both well and compactly. All that I can recommend, therefore, is that you read the book.

FORGIVING

'Anderson, Robert. After (a novel). New York: Random House, 1973. Anderson is one of the finest playwrights of our time, and now rates as a novelist. He combines exquisite sensitivity and perception with superb writing craftsmanship. He writes of the ordeal of a man whose wife has died of breast cancer. He relives her dying and his subsequent attempts to adjust to her loss and resume the business of living. His "Christopher Larsen" (his main character) is the brother of every man who has ever lost a wife. The people are alive in this superb noveL

SCIENTISTS, RESEARCH AND DISCOVERY

Barber, B. "Resistance by Scientists to Scientific Discovery." Science 34 (1961): 596-602.
Chargaff, E. "Preface to a Grammar of Biology." Science 172 (1971 ): 637-642. This is a wonderful, wise, and well-written essay on the "state of the art" of biology. Chargaff is the man who made the discovery of the base ratios in DNA. I thought of reprinting it verbatim, but decided not to because my book might suffer by the comparison.
Dunn, T. B. "The Value of Animal Research, and the Men Who Do this Research." Cancer Research 22 (1962): 898-905. A warm and great lady of cancer research talks about people.
Greenberg, Daniel S. The Politics of Pure Science. New York:New American Library, 1967.
Stewart, H. L. "The Cancer Investigator." Cancer Research 1959): 804-818. A humorous and wonderful essay describing the cancer research scientist's utopia, and the author's personal philosophy; one of the finest bits of literature ever published in a cancer journal.

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