Ambrose, E. J., and Roe, F. J. C. The Biology of Cancer. London and Princeton, N.J.: D. Van Nostrand, 1966. (Fairly technical)
Berenblum, I. Cancer Research Today. London: Pergamon Press 1967. Written from the scientist's point of view. Reasonably detailed, but makes fairly easy reading. Particularly valuable to someone with a background in biology.
Cameron, C. S. The Truth About Cancer. New York: Collier Books, 1967. A book for the layman written from the point of view of the physician. It has a good deal of information about specific forms of cancer. There is an outstanding section on cancer quackery, and much good advice on things such as breast self-examination.
Foulds, L. Neoplastic Development. London: Academic Press, 1969. The historical review in this book is worth reading by the physician or the biologist for an overview of the field of experimental cancer research. It is written for the specialist rather than the layman.
Leighton, J. The Spread of Cancer. New York and London: Academic Press, 1967. An excellent book on the spread of cancer (metastasis) written for the professional.
McGrady, Pat. The Savage Cell. New York: Basic Books, 1964. Easy reading about cancer research. McGrady is a professional science writer, and it shows. It contains a large amount of information in easily digestible form.
Perez-Tamayo, R. Mechanisms of Disease: An Introduction to Pathology. Philadelphia: W. B. Saunders, 1961. A remarkably concise discussion of tumors, intended for the student of pathology and the specialist. It has a very discriminating synthesis of clinical observation and experimental cancer research.
Shimkin, Michael B. Science and Cancer, Public Health Service Publication No. 1162, 1969. Very easy reading, highly informative, and concise book. It says an awful lot in150 pages.
(All highly technical)
Leblond, C. P. "Classification of Cell Populations on the Basis of Their Proliferative Behavior," in Control of Cell Division and the Induction of Cancer, Monograph 14. Bethesda, Md.: National Cancer Institutes, 1964, pp.119-149.
Pilgrim, H. I. "The Kinetics of the organ-specific Metastasis of a Transplantable Reticuloendothelial Tumor." Cancer Research 29(1969): 1200-1205.
The Proliferation and Spread of Neoplastic Cells. Baltimore: Williams and Wilkins, 1968, 794 pages. A collection of papers on the spread and growth of tumors.
The following two references refer to the work of Rous and Huggins that won them the Nobel Prize. They are both fairly technical.
Rous, F. P. "The Challenge to Man of the Neoplastic Cell" (Nobel Prize Lecture). Cancer Research 27 (1967): 1919-1924; also in Science 157(1967): 24-28.
Huggins, C. B, "Endocrine-induced Regression of Cancers (Nobel Prize Lecture). Cancer Research 27 (1967): 1925-1930.
Oberling, Charles. The Riddle of Cancer. New Haven, Conn.: Yale University Press,1944. This book is written by a French scientist and represents the point of view of some one who believes very strongly that cancer is caused by viruses. It is well written, well translated, and makes fairly easy reading. One of the most interesting parts of the book is his discussion of the series of events that led up to Fibiger winning the Nobel Prize, and the events following that indicated that his results were not repeatable. Oberling retains his objectivity throughout the book despite his being an adherent of the virus theory of cancer.
Watson, J. D. Molecular Biology of the Gene. New York: W. A. Benjamine, 1965. This is a book for students of molecular biology. Two simpler, more readable books are listed below.
Asimov, I. The Genetic Code. New York: New American Library, 1963.
Frankel, E. DNA --Ladder of Life. New York: McGraw-Hill, 1964.
(All highly technical)
Blum, H. F. Carcinogenesis By Ultraviolet Light. Princeton, N.J.: Princeton University Press, 1959.
Brues, A. M. "Critique of the Linear Theory of Carcinogenesis." Science 128 (1958): 693-699. A very thorough discussion in which the author concludes that the relationship of radiation to carcinogenesis is probably not linear, and that there is probably a threshold below which no leukemia is induced.
Folley, J. H., Borges, W., and Yamawaki, T. "Incidence of Leukemia in Survivors of the Atomic Bomb in Hiroshima and Nagasaki, Japan." American Journal of Medicine (1952): 311-321.
Fraumeni, J. F., Miller, R. W. "Epidemiology of Human Leukemia: Recent Observations." Journal of National Cancer Institute 38 (1966): 593-605. A very thorough discussion of leukemia statistics.
Furth, J., and Upton, A. C. "Vertebrate Radiobiology: Histopathology and Carcinogenesis." Annual Review of Nuclear Science 3 (1953) 303-337. A fairly complete review of the subject.
Hemplemann, L. H., Pifer, J. W., Burke, G. J., et al.: "Neoplasms in Persons Treated with X-rays in Infants for Thymic Enlargement. A Report of the Third Follow-up Survey." Journal of National Cancer Institute 38 (1967):317-341. A complete follow-up study of infants that had received thymic irradiation.
Lewis, E. B. "Leukemia, Multiple Myeloma, and Aplastic Anemia in American Radiologists." Science 142 (1963): 1492-1494.
Mays, C. W. "Cancer induction in man from internal radioactivity." Health Physics 25 (1973): 585-592. A delight fully written short summary of the work which has been done on cancer caused by the ingestion, inhalation or injection of radioactive substances. Mays is one of a group of quiet people who are providing the accurate information which the public need to become justifiably outraged.
Mays, C. W., and Lloyd, R. D. "Bone Sarcoma Risk for 90Sr." 1971, in press.
Moloney, W. C., and Lange, R. D. "Leukemia in Atomic Bomb Survivors II. Observations on Early Phases of Leukemia." Hematology 9 (1954): 663-684.
Simpson, C. L., and Hemp]emann, L. H. "The Association of Tumors and Roentgen Ray Treatment of the Thorax in Infancy." Cancer 10 (1957): 42-56.
Gurdon, J. B. Transplanted Nuclei and Cell Differentiation. Scientific American 219 (1968): 24-35.
Kleinsmith, L. J., and Pierce, G. B. "Multipotentiality of Single Embryonal Carcinoma Cells." Cancer Research 24 (1964):1544-1551.
Stevens, L. C. "Experimental Production of Testicular Teratomas in Mice of Strains 129, A /He, and Their F1 hybrids." Journal of National Cancer Institute 44 (1970): 923-929.
Symposium sponsored by the American Cancer Society. "The Developmental Biology of Neoplasia." Cancer Research 28(1967): 1797-1914.
Clemens, S. (Twain, M.) Tom Sawyer, 1875. The classic paper on wart treatment.
(The following are all highly technical)
Giertsen, J. C. "Malignant Testicular Tumors Following Mumps Orchitis." Acta Pathologica et Microbiologica Scandinavica 42 (1957): 7-14.
Gross, L. Oncogenic Viruses. New York: Pergamon Press, 1961.
Melnick, J. L. 1965 "The Papovavirus Group," in Viral and Rickettsial Infections of Man, 4th ed. Edited by Horsfall and Tanner. Philadelphia: J. B. Lippincott Co., 1965, pp. 841-859.
Prehn, R. T. "Tumor-specific Antigens of Putatively Nonviral Tumors." Cancer Research 28 (1968): I326-I33O.
Rowe, Wallace P. "1973 Genetic Factors in the Natural History of Murine Leukemia Virus Infection." Cancer Research 33: 3061-3068. A fine, highly technical history and discussion of the cancer-virus-gene problem. Rowe and his group perform highly competent virus-cancer research at the National Institute of Allergy and Infectious Diseases; a stone's throw from the political hubbub of the National Cancer Institute.
Symposium sponsored by the American Cancer Society. "Conference on Tumor-specific Antigens." Cancer Research 28(1967): 1275-1459.
_Conceptual Advances in Immunology and Oncology. New York: Harper & Row. Hoeber Medical Division, 1963. This volume contains the papers from a symposium on "Fundamental Cancer Research" held at the M. D. Anderson Hospital and Tumor Institute in Houston, Texas. Among many interesting (and very technical) articles are papers by Hans 0. Sjogren (Sweden) and by Karl Habel (U.S.A.), who independently discovered the immunologic differences in polyoma-induced tumors. There is also a paper by R. H. Wilson et al. on treating human cancer with concentrated antibodies.
Jacobs, Barbara B., and Huseby, R. A. "Growth of Tumors in Allogeneic Hosts Following Organ Culture Explantation." Transplantations (1967): 410-419.
(Both highly technical)
Clark, W. H., Jr., From, L., Bernadino, E. A., et al: Histogenesis and Biologic Behavior of Primary Human Malignant Melanomas 0f the Skin." Cancer Research 29(1969): 705-726.
Wintrobe, M. M. Clinical Hematology, 6th ed. Philadelphia: Lea & Febiger,1967.
The following two books document a goodly number of cases of "proved" cancer that either went into long remission, or where the cancers disappeared completely. Many of the cases that have undergone spontaneous remissions and cures have been some of the rarer types of cancer in children, the so called embryonic tumors.
Boyd, W. The Spontaneous Regression of Cancer. Springfield, Charles C Thomas, 1966.
Everson, T. C., and Cole, W. H. Spontaneous Regression of Cancer. Philadelphia and London: W. B. Saunders, 1966.
Campion, Rosamond. The Invisible Worm. New York. Macmillan Co., 1972. This book tells of the personal experience of a woman with breast cancer. She also discusses the experiences of her acquaintances who have had breast cancer. It is a well-written, well thought-out book. She chose to go to George Crile for a lumpectomy. She summarizes her opinion as follows: "The truth is this: no woman on earth is exactly like any other woman. Even in the thrall of a dread disease, she is unique and must be paid by her doctor the compliment of being allowed partnership, within the proper framework of her illness, in deciding what is the best solution for her own special or even eccentric needs."
Crile, G. A Biological Consideration of Treatment of Breast Cancer. Springfield, Ill.: Charles C. Thomas, 1967. Advocates simple surgery and a "common sense" approach to cancer.
Crile, George. What Women Should Know About the Breast Cancer Controversy. New York: Macmillan Co., 1973. I read this book while putting the finishing touches on this manuscript. There was no need to change a word in my book, because Crile's conclusions and mine are almost the same. Crile writes well, and his understanding of surgery is profound. He does not believe in the efficacy of radical mastectomy, and prefers simple mastectomy or modified radical mastectomy. He does not, as has been implied in a newspaper article that I have read, "advocate" lumpectomy except for the woman who is willing to risk her life to save her breast. He believes that the patient has the right to make his or her own decisions. He did point out something which I had completely overlooked: that the amount of money paid to a surgeon by an insurance company is proportional to the amount of work involved rather than the efficacy of the operation. I phoned my local Blue Shield office and found out that a simple mastectomy is twice as lucrative as a lumpectomy or partial mastectomy and that a radical is two and a half times as lucrative as a simple mastectomy.
Fisher, B. "The Surgical Dilemma in the Primary Therapy 0f Invasive Breast Cancer: A Critical Appraisal." Current Problems in Surgery:Chicago: Year Book Medical Publishers, October 1970, 53 pages. A scholarly, complete, and objective review of the literature. This is "must reading" for the surgeon. He concludes that surgeons should continue with their usual method of treatment until the critical trials have been performed; and these trials are long overdue. They have been started in England, and are being started in this country.
"Conference on Acute Leukemia and Burkitt's Tumor," Cancer Research 27 (1967): 2414-2660. A series of papers on leukemia and Burkitt's tumor.
Holland, J. F. "Progress in the Treatment of Acute Leukemia, 1966." Perspectives in Leukemia. New York: Grune & Stratton, 1968, pp.217-240.
In the journal Cancer Research, vol.29, no.12 (November 1969) pages 2262-2485, there is a many-authored discussion of the present state of chemotherapy. Good results have been obtained with the following tumors: Choriocarcinoma, Wilms' tumor (a tumor of the kidney that occurs in children), tumors of the testicle, Burkitt's lymphoma (a lymphocytic tumor which also occurs frequently in children), and Hodgkin's disease.
Cameron, C. S. The Truth About Cancer. Englewood Cliffs, N.J.: Prentice Hall, 1956; Also New York: Macmillan Co., 1967. His chapter on the cancer quack is a gem.
Groddeck, Georg. Das Buch Von Es. Vienna: International Psychoanalytischer Verlag, 1923. This book is available in paperback, in an excellent translation as The Book of the It. New York: New American Library, Mentor Books, 1961. Groddeck has been called the "father of psychosomatic medicine." He was a contemporary of Freud. Although he was a friend and admirer of Freud, he was never a true disciple. He went his own way and made many original observations (see Carl and Sylva Grossman, The Wild Analyst. New York: Dell Publishing Co., 1965). Groddeck has no fancy theoretical constructs to obscure his astute observations. He is a humane physician who is also exquisitely perceptive and an excellent writer. The simplicity of this book is not only deceptive, but seductive. In the words of a young friend of mine. "It's a real mind blower."
Crile, G. Cancer and Common Sense. New York: Viking Press, 1955. This is a wonderful and readable book by a surgeon. It is delightful reading and full of wisdom and under standing. It has raised some hackles by statements such as, "Those responsible for telling the public about cancer have chosen to use the weapon of fear. They have portrayed cancer as an insidious, dreadful, relentless invader. With religious fervor they have fashioned a devil out of cancer. They have bred in a sensitive public a fear that is approaching hysteria. They have created a new disease, cancerphohia, a contagious disease that spreads from mouth to ear. It is possible that today cancerphobia causes more suffering than cancer itself." Page 7.
This book was written at a time surgeons were doing super-radical operations that have now been largely discredited. It is already a classic, and is must reading" for physicians, patients, and anyone who is interested in disease and the human being.
Kubler-Ross, Elisabeth. On Death and Dying. New York: Macmillan Co., 1969. (This is available in paperback) This book is by a psychiatrist who has been working with the terminally ill. It is a very readable book, and should be "must reading" for all physicians and clergymen. It describes how people react to serious illness. One of the underlying themes, which isn't specifically stated, appears to be "Physician, heal thyself." It is a sensitive, wise, and understanding book.I tried to summarize this book in an attempt to give the reader the essence of what is said in it. I found myself removing so many large quotations, that I would feel that I would have had to pay Dr. Kubler-Ross royalties for taking that much. It is not very useful to try to summarize something that is already said both well and compactly. All that I can recommend, therefore, is that you read the book.
'Anderson, Robert. After (a novel). New York: Random House, 1973. Anderson is one of the finest playwrights of our time, and now rates as a novelist. He combines exquisite sensitivity and perception with superb writing craftsmanship. He writes of the ordeal of a man whose wife has died of breast cancer. He relives her dying and his subsequent attempts to adjust to her loss and resume the business of living. His "Christopher Larsen" (his main character) is the brother of every man who has ever lost a wife. The people are alive in this superb noveL
Barber, B. "Resistance by Scientists to Scientific Discovery." Science 34 (1961): 596-602.
Chargaff, E. "Preface to a Grammar of Biology." Science 172 (1971 ): 637-642. This is a wonderful, wise, and well-written essay on the "state of the art" of biology. Chargaff is the man who made the discovery of the base ratios in DNA. I thought of reprinting it verbatim, but decided not to because my book might suffer by the comparison.
Dunn, T. B. "The Value of Animal Research, and the Men Who Do this Research." Cancer Research 22 (1962): 898-905. A warm and great lady of cancer research talks about people.
Greenberg, Daniel S. The Politics of Pure Science. New York:New American Library, 1967.
Stewart, H. L. "The Cancer Investigator." Cancer Research 1959): 804-818. A humorous and wonderful essay describing the cancer research scientist's utopia, and the author's personal philosophy; one of the finest bits of literature ever published in a cancer journal.